Stocks to Crash on March 16, 2026? Here's Compelling Reason Why

Perhaps no one on or off Wall Street has been more accurate calling the bull and bear turns of the past 7 years. From the bear markets of 2018 and 2022... to the roaring bull runs of 2021, 2023, and 2024. And now, Marc Chaikin is predicting the next crash will start March 14, 2026. If you have money in the markets, Chaikin's thesis is a must-see.

Eventful Monday For AstraZeneca - What's Going On?

Vandana Singh
March 17, 2025

On Monday, AstraZeneca Plc (NASDAQ:AZN) released high-level results from the CALYPSO Phase 3 trial designed to evaluate the efficacy and safety of eneboparatide in adults with chronic hypoparathyroidism.

The study showed that eneboparatide (AZP-3601), an investigational parathyroid hormone (PTH) receptor 1 agonist, met its primary endpoint with statistical significance at 24 weeks in adults with chronic hypoparathyroidism (HypoPT) compared to placebo.

The primary endpoint is a composite of normalization of albumin-adjusted serum calcium levels and independence from active vitamin D and oral calcium therapy.

Also Read: AstraZeneca’s Imfinzi-Based Regimen Shows Improved Event-Free Survival In Early-Stage Gastric Cancer Patients

HypoPT is a rare endocrine disease caused by a deficiency of PTH and is characterized by impaired regulation of calcium and phosphate levels in the blood. Eneboparatide was well tolerated.

After the 24-week randomized treatment period, all patients receive eneboparatide in the ongoing long-term extension until 52 weeks. Full efficacy and safety data will be analyzed at 52 weeks.

Concurrently, AstraZeneca and Alteogen entered into an exclusive license agreement for ALT-B4, a hyaluronidase utilizing Hybrozyme platform technology.

Under the terms of the agreement, AstraZeneca will acquire worldwide rights to use ALT-B4 to develop and commercialize subcutaneous formulations of several oncology assets.

Alteogen will be responsible for the clinical and commercial supply of ALT-B4 to AstraZeneca.

AstraZeneca will pay Alteogen an upfront payment and additional payments upon achieving specific development, regulatory, and sales-related milestones. Additionally, Alteogen will receive royalties on the sales of the commercialized products.

On Monday, the European Union approved AstraZeneca’s Imfinzi (durvalumab) as monotherapy for adults with limited-stage small cell lung cancer whose disease has not progressed following platinum-based chemoradiation therapy.

The approval is based on results from the ADRIATIC Phase 3 trial.

The trial showed that Imfinzi reduced the risk of death by 27% compared to placebo.

The estimated median overall survival was 55.9 months for Imfinzi versus 33.4 months for placebo. An estimated 57% of patients treated with Imfinzi were alive at three years compared to 48% for placebo.

Imfinzi also reduced the risk of disease progression or death by 24% versus placebo.

The median progression-free survival (PFS) was 16.6 months for Imfinzi versus 9.2 months for placebo. An estimated 46% of patients treated with Imfinzi had not experienced disease progression at two years compared to 34% for placebo.

Earlier on Monday, AstraZeneca agreed to acquire cell therapy focused-EsoBiotec SA for up to $1 billion.

Price Action: At the last check on Monday, AZN stock was down 1.04% to $76.78 during the premarket session.

Read Next:

  • Hain Celestial Valuation Is Low Versus Historical Levels, But Analyst Remains Neutral – Here’s Why

Image by Robert Way via Shutterstock

Continue Reading...

Popular

The UK is cutting welfare spending to urge people to work. Critics say it will hurt the vulnerable

LONDON (AP) — Britain’s Labour Party government on Tuesday announced an overhaul of the welfare system that it says will save the 5 billion pounds ($6.5 billion). Critics claim it will harm some of the U.K.’s most vulnerable people.

Mortgage lender Rocket Cos. to acquire real estate brokerage Redfin in deal valued at $1.75 billion

Mortgage lender Rocket Cos. has agreed to acquire online real estate brokerage Redfin in an all-stock deal valued at $1.75 billion.

The Last Time Gold Flashed This Warning Sign, the Market Dropped 80% - Ad

Both President Trump and Elon Musk are warning about something that could send the market down 50%, real estate down 40% and savings accounts down 30%.

Why should America worry about Trump? Try the price of eggs, say some Democrats

NEW YORK (AP) — As their party struggles to navigate the early days of Donald Trump's second presidency, some Democrats are convinced that their road to recovery lies in the price of eggs.

AI pioneers who channeled 'hedonistic' machines win computer science's top prize

Teaching machines in the way that animal trainers mold the behavior of dogs or horses has been an important method for developing artificial intelligence and one that was recognized Wednesday with the top computer science award.

13-Second Trump Video Could Trigger AI Shock - Ad

Louis Navellier, the legendary investor who picked Nvidia before shares exploded as high as 3,423%... Just released a video with this 13-second Trump clip about the current AI boom. Please, do NOT buy any AI stock before watching that clip. What President Trump said in that clip could have implications for this AI boom.

Trump Organization Sues Capital One Over Alleged Political Bias in Account Closures, Eric Trump Leads Charge

The Trump Organization has launched a lawsuit against Capital One, alleging that the bank closed hundreds of Trump-linked accounts for politically motivated reasons.

Massive Losses For Crypto Traders As MELANIA Memecoin Plummets

A crypto trader has reportedly suffered a staggering loss of $15.68 million after trading the official memecoin of First Lady Melania Trump.

The Gold Shift No One's Talking About - Yet - Ad

Massive gold shipments are quietly moving from London to the U.S.--no headlines, no explanations. Could a full-scale audit or a new gold-backed system be coming? Smart money isn't waiting. My gold strategy is already doubling physical gold's returns this year.

Cathie Wood-Led Ark Invest Roblox, Roku, UiPath As Markets Take A Dip

Ark Invest made significant trades on Friday, selling shares of RBLX, ROKU, PATH and buying shares of IBTA, PSNL, ABSI, and RXRX.

Prices rose along border ahead of Trump's tariffs - now disruption looms

As are set to take effect on Tuesday, Hispanic-owned businesses and companies that depend on cross-border trade are already passing higher prices onto consumers and preparing to sharply reduce imports.

Warning: What They Haven't Told You (Yet) About the 2025 Selloffs - Ad

In light of massive recent selloffs... Stansberry Research has issued a new warning for the public. Their latest research shows the real truth about the 2025 tariff selloffs is much bigger -- and much worse -- than the public realizes. They say unless you take the right steps now... You could soon see your wealth cut in half.

Trudeau slams Trump's tariffs, says US is appeasing Putin while launching a trade war against Canada

TORONTO (AP) — Canadian Prime Minister Justin Trudeau called “very dumb” and said that U.S. President Donald Trump is appeasing Russia while launching a trade war against Canada.

Mexican finance minister, a holdover from previous administration, resigns and is replaced by deputy

MEXICO CITY (AP) — Mexican Finance Secretary Rogelio Ramírez de la O, a holdover from the previous administration, resigned Friday for personal reasons and will be replaced by his deputy, President Claudia Sheinbaum said.

Just Released: Huge New A.I. Trade - Ad

While everyone's distracted by Nvidia, PLTR & Bitcoin, billionaires have been quietly loading up on this stock. And 99% of Americans have no clue. It could help make a fortune for fast-moving investors, who make their move before May 13th.

Trump's tariff tactics carry higher economic risks than during his first term

WASHINGTON (AP) — When Donald Trump started the biggest trade war since the 1930s in his first term, his impulsive combination of threats and import taxes on U.S. trading partners created chaos, generated drama -- and drew criticism from mainstream economists who favor free trade.

Mexico to impose retaliatory tariffs on US following China and Canada as trade war heats up

MEXICO CITY (AP) — Mexico President Claudia Sheinbaum said Tuesday that Mexico will respond to with its own retaliatory tariffs on U.S. goods.

Trump's Secret Plan to Reboot the Dollar Leaked? - Ad

Steve Bannon let slip 3 shocking words--and Wall Street panicked. According to Bannon, President Trump is poised to restore the gold standard, reset the dollar, and send gold soaring. Position yourself before it's too late! Claim your free 2025 Gold Guide and discover the Trump Loophole to move funds from your IRA & 401(k) into gold--tax-free!

Europe-Based UCB's Bimzelx Data Reveals Sustained Skin Clearance In Inflammatory Skin Disorders

UCB's Bimzelx shows sustained efficacy in psoriasis and hidradenitis suppurativa, with high skin clearance rates and improved symptoms over long-term trials.

Major retailers tamper expectations for 2025 as Americans slow their spending

A pullback by American shoppers has led to more caution from national retailers about their sales potential in 2025, Abercrombie & Fitch on Wednesday becoming the latest.

DOGE's Next Target Set To Hand 401K Savers A Windfall? - Ad

Musk's Department of Government Efficiency has already uncovered $55B in waste--and Trump's backing his plan to return $2T in savings to taxpayers. But why wait? Unlock a legal Trump IRS loophole to protect & grow your wealth NOW!

Palantir's Head Of Defense Warns Of China's War Preparations: 'We're Not Taking It Seriously'

Palantir Technologies Inc. Head of Defense and former Congressman Mike Gallagher is sounding alarms about China's military intentions, warning that the U.S. is failing to adequately prepare for potential conflict.

Cathie Wood Stands By 'Deflationary Boom' Call As Gene Munster Compares Market Turmoil To Dot-Com Bubble

Ark Funds CEO Cathie Wood forecasts a "deflationary boom" as markets tumbled on Monday, with the Magnificent Seven tech stocks shedding approximately $780 billion in market capitalization.

Three New Patents Reveal Elon and Trump's Secret "Project America" - Ad

Three patents could help President Trump and Elon Musk completely revolutionize a $23 Trillion market. This revolution is about so much more than just self-driving cars. Instead, what Elon's pivoting Tesla towards... Is a market that's 1,000X BIGGER. But a project THIS big can't stay under the radar for long...

Japan's Seven & i sells retail business to Bain Capital for $5.4 billion, plans IPO

Japan’s Seven & i, the parent company of the Japanese 7-Eleven convenience store chain, said Thursday it is selling its supermarket store assets to Bain Capital for about $5.4 billion.

What's Going On With SoundHound AI Stock Friday?

SoundHound shares are moving higher on Friday after the company announced it will participate in the 2025 Nvidia GPU Technology Conference.

Claim the "No.1 Coin of 2025" Before March 24th - Ad

After spotting 44 different coins that have returned over 100%...Chris Rowe is now exposing the details behind the "Superpower Coin"... that's partnered with 19 of the largest companies from some of the world's largest superpower nations... A little-known 3-cent coin that is poised to outperform Bitcoin in 2025... starting on March 24th.

Mark Carney Takes Justin Trudeau's Job As Canada's New PM, Ready to Face Trump's Tariff Threats: 'I Know How To Manage Crises'

Mark Carney, a former central banker with no prior political experience, is set to become Canada's prime minister, tasked with navigating trade tensions and Trump's tariffs.

Facing competition from Big Tech, states dangle incentives and loosen laws to attract power plants

HARRISBURG, Pa. (AP) — Facing projections of spiking energy demand, U.S. states are pressing for ways to build new power plants faster as policymakers increasingly worry about protecting their residents and economies from rising electric bills, power outages and other consequences of falling behind Big Tech in a race for electricity.

Trump's Economic Plan Is Driving a "Golden Anomaly" in Tiny Gold Miners - Ad

Trump's plan to revalue gold and decrease the US debt burden is causing a major dislocation in four small gold miners. Some 30 million ounces of gold have left London for the US. If you want to know why - and why four little-known gold miners are up 136% in just the last 12 months while major gold ETFs have barely moved...

India's steel industry contemplates potential fallout from Trump administration tariffs

BENGALURU, India (AP) — Rows of small factories line the streets of a dusty suburb in Bengaluru, where workers weld and cast Indian-made steel into everything from car parts to kitchen sinks. Here, U.S. President Trump’s announcement to on steel imports has some unexpected supporters.

Exposed: 3 Cent Crypto to Explode March 24th? - Ad

Chris Rowe, the man who spotted 44 different coins that have returned over 100%, is now making the biggest crypto call of his ENTIRE career.... Because a powerful crypto event will trigger on March 24th... Sending hundreds of tiny cryptos soaring 5X, 50X, even 100X -- in just days.

Freshpet Is Not Out Of The Woods On Consumption Trends, Analyst Says

JP Morgan analyst cuts Freshpet price forecast to $102 while maintaining a Neutral rating. Concerns over changing consumption trends and accuracy of estimates, but strong revenue growth and long-term potential. EBITDA and revenue growth estimates revised.

Trump tells crypto leaders at White House summit he's committed to helping their industry

President Donald Trump said Friday he’s committed to making the U.S. as industry leaders heaped praise on him for reversing what they said had been unfair attacks on digital assets by the previous administration.

Millionaire Trader: "My No. 1 Stock of the Decade" (Revealed Free) - Ad

The stock revealed right here just may be millionaire trader Jeff Clark's favorite stock ever. Because this one stock alone has been responsible for some of the biggest gains he's ever handed my readers... 195% in under a month... 85% in 14 days... 176% in 5 weeks... 120% in under 3 months... 55% in two days... 138% in 8 days... And even 222% in 8 days.

Bristol Myers Acquired MyoKardia Drops Fulcrum Agreement, Ending Cardiomyopathy Research Deal

MyoKardia, a Bristol Myers unit, is terminating its agreement with Fulcrum Therapeutics, ending a cardiomyopathy research deal set to expire in June 2025.

China's foreign minister blasts the US over tariffs at his annual meeting with journalists

TAIPEI, Taiwan (AP) — Along with against the United States, China’s Foreign Minister Wang Yi reasserted China’s South China Sea claims, blasted Japan for its past aggression and covered a wide range of other issues during his annual meeting with the press. Here are some of the key topics covered during his Friday press conference.

Warren Buffett's Investing Partner's Shocking Final Move - Ad

Before he passed away, Charlie Munger, Warren Buffett's investing partner of 60 years, was rumored to have quietly made one final investment... Up until now, it has remained hidden from the public. It's potentially the smartest, most profitable, and most under-valued AI investment you can make today.

Apple Delays Next-Gen Siri: 'It's Going To Take Us Longer Than We Thought' To Deliver AI Upgrades

Apple has delayed its next-gen Siri upgrade, citing the need for more development time, while internal reports suggest significant issues could push the AI-powered features back until iOS 20 or later.

Trending Now

Information, charts or examples are for illustration and educational purposes only and not for individualized investment management This message contains commercial elements, such as advertising. We only send these offers to those who have opted in to our newsletter. Past performance is not indicative of future results. For these reasons we strongly suggest trading in a DEMO/Simulated account. The information provided by us is for educational and informational purposes only. We make no representations or warranties concerning the products, practices or procedures of any company or entity mentioned or recommended and have not determined if the statements and opinions of the advertiser are accurate, correct or truthful. If you use, act upon or make decisions in reliance on information contained or any external source linked within it, you do so at your own peril and agree to hold us, our officers, directors, shareholders, affiliates and agents without fault.

Copyright technicaltrading.org
Privacy Policy | Terms of Service