The $20 Trillion Secret of Room 3330

Developed by the U.S. military 79 years ago, this controversial technology is about to change American life forever: Elon Musk has already funneled $6 billion to resurrect this covert project -- and the companies involved are minting 10,000 millionaires every week [Goldman Sachs].

Eventful Monday For AstraZeneca - What's Going On?

Vandana Singh
March 17, 2025

On Monday, AstraZeneca Plc (NASDAQ:AZN) released high-level results from the CALYPSO Phase 3 trial designed to evaluate the efficacy and safety of eneboparatide in adults with chronic hypoparathyroidism.

The study showed that eneboparatide (AZP-3601), an investigational parathyroid hormone (PTH) receptor 1 agonist, met its primary endpoint with statistical significance at 24 weeks in adults with chronic hypoparathyroidism (HypoPT) compared to placebo.

The primary endpoint is a composite of normalization of albumin-adjusted serum calcium levels and independence from active vitamin D and oral calcium therapy.

Also Read: AstraZeneca’s Imfinzi-Based Regimen Shows Improved Event-Free Survival In Early-Stage Gastric Cancer Patients

HypoPT is a rare endocrine disease caused by a deficiency of PTH and is characterized by impaired regulation of calcium and phosphate levels in the blood. Eneboparatide was well tolerated.

After the 24-week randomized treatment period, all patients receive eneboparatide in the ongoing long-term extension until 52 weeks. Full efficacy and safety data will be analyzed at 52 weeks.

Concurrently, AstraZeneca and Alteogen entered into an exclusive license agreement for ALT-B4, a hyaluronidase utilizing Hybrozyme platform technology.

Under the terms of the agreement, AstraZeneca will acquire worldwide rights to use ALT-B4 to develop and commercialize subcutaneous formulations of several oncology assets.

Alteogen will be responsible for the clinical and commercial supply of ALT-B4 to AstraZeneca.

AstraZeneca will pay Alteogen an upfront payment and additional payments upon achieving specific development, regulatory, and sales-related milestones. Additionally, Alteogen will receive royalties on the sales of the commercialized products.

On Monday, the European Union approved AstraZeneca’s Imfinzi (durvalumab) as monotherapy for adults with limited-stage small cell lung cancer whose disease has not progressed following platinum-based chemoradiation therapy.

The approval is based on results from the ADRIATIC Phase 3 trial.

The trial showed that Imfinzi reduced the risk of death by 27% compared to placebo.

The estimated median overall survival was 55.9 months for Imfinzi versus 33.4 months for placebo. An estimated 57% of patients treated with Imfinzi were alive at three years compared to 48% for placebo.

Imfinzi also reduced the risk of disease progression or death by 24% versus placebo.

The median progression-free survival (PFS) was 16.6 months for Imfinzi versus 9.2 months for placebo. An estimated 46% of patients treated with Imfinzi had not experienced disease progression at two years compared to 34% for placebo.

Earlier on Monday, AstraZeneca agreed to acquire cell therapy focused-EsoBiotec SA for up to $1 billion.

Price Action: At the last check on Monday, AZN stock was down 1.04% to $76.78 during the premarket session.

Read Next:

  • Hain Celestial Valuation Is Low Versus Historical Levels, But Analyst Remains Neutral – Here’s Why

Image by Robert Way via Shutterstock

Continue Reading...

Popular

Judge blocks Trump administration from terminating $14 billion in 'green bank' grants

WASHINGTON (AP) — A federal judge on Tuesday blocked the Trump administration from terminating $14 billion in grants awarded to three climate groups by the Biden administration, saying the government's “vague and unsubstantiated assertions of fraud are insufficient.”

Warning: What They Haven't Told You (Yet) About the 2025 Selloffs - Ad

In light of massive recent selloffs... Stansberry Research has issued a new warning for the public. Their latest research shows the real truth about the 2025 tariff selloffs is much bigger -- and much worse -- than the public realizes. They say unless you take the right steps now... You could soon see your wealth cut in half.

Sam Bankman-Fried Says 'When Rubber Meets The Road' On Crypto's Fate Under Trump, Slams Biden's Policies

Disgraced cryptocurrency mogul Sam Bankman-Fried weighed in on the future of digital assets under President Donald Trump’s administration, according to an interview from his prison released Thursday.

Apple Supplier Foxconn Unveils AI Model Using Nvidia Tech

Foxconn built AI model FoxBrain in 4 weeks with reasoning capabilities, aiming to advance manufacturing and supply chain management.

Warren Buffett's Investing Partner's Shocking Final Move - Ad

Before he passed away, Charlie Munger, Warren Buffett's investing partner of 60 years, was rumored to have quietly made one final investment... Up until now, it has remained hidden from the public. It's potentially the smartest, most profitable, and most under-valued AI investment you can make today.

What's Going On With Ford Stock Wednesday?

Investors may be assessing trade policy along with President Donald Trump's plan to make interest payments on automobile loans tax deductible for US-made vehicles.

Asian shares slip as investors brace for further uncertainty over tariffs, await US jobs report

BANGKOK (AP) — Asian shares were mostly lower on Friday, with Tokyo’s benchmark down more than $2 after a on Wall Street.

The 2025 'Trump Shock' [401K Owners Stunned] - Ad

Trump's Gold Reset? A massive dollar overhaul could be coming! Insiders say Trump may return America to the gold standard--sending gold prices soaring. He's been stockpiling gold for decades... should you? Discover how to legally move funds from your IRA & 401(k) into gold tax-free!

Microsoft Pours $297 Million Into AI And Cloud Expansion In South Africa

Microsoft to invest $297 million to expand cloud and AI infrastructure in South Africa, enabling organizations to access solutions and certifications in digital skills.

Trump's Secret Plan to Reboot the Dollar Leaked? - Ad

Steve Bannon let slip 3 shocking words--and Wall Street panicked. According to Bannon, President Trump is poised to restore the gold standard, reset the dollar, and send gold soaring. Position yourself before it's too late! Claim your free 2025 Gold Guide and discover the Trump Loophole to move funds from your IRA & 401(k) into gold--tax-free!

Broadcom Shares Jump 13% In After-Hours Trading On Strong AI Results - Gary Black Says, 'This Should Help AI Stocks Tomorrow

Broadcom Inc. shares jumped 12.82% in after-hours trading Thursday after reporting better-than-expected first-quarter results, recovering from a 6.33% drop during regular trading hours amid a broader artificial intelligence chip selloff.

Greenland in facts and figures

NUUK, Greenland (AP) — is having a moment in the spotlight as U.S. President Donald Trump maneuvers to gain control of the mineral-rich Arctic country. Here are some facts and figures about it:

The "Second Wave" of 2025 Crashes (Could Be Worst in Us History) - Ad

According to the man who predicted 2008, 2020, and 2022... A new wave of crashes are coming to the US stock market. But these will be different. The moment they hit, they could kick off the worst (and longest) financial crisis in American history.

Alibaba Unveils New AI Chip To Power China's Open-Source Tech Push, Challenge US Chip Giants

Alibaba's new processor, XuanTie C930, boosts China's semiconductor industry by promoting open-source chips & AI acceleration, amid US sanctions.

Washington Won't Save You--but This 4-Step Plan Might - Ad

America's economy is unraveling--soaring costs, skyrocketing debt, and Wall Street insiders dumping stocks. This isn't a recession--it's an economic breakdown. Stocks could crash 50%, real estate 40%, and inflation will eat your savings. But history shows: the biggest crashes create the biggest fortunes--if you act now!

Canada to name a new leader while dealing with Trump trade war

TORONTO (AP) — looks set to pick a measured former central banker to deal with the threats tariffs pose against a pillar of Western free trade.

CDC Considers New Autism Study As Vaccine Safety Debate Persists

The CDC is planning a large study on potential vaccinAutism's links, despite extensive research dismissing any connection.

Millionaire Trader: "My No. 1 Stock of the Decade" (Revealed Free) - Ad

The stock revealed right here just may be millionaire trader Jeff Clark's favorite stock ever. Because this one stock alone has been responsible for some of the biggest gains he's ever handed my readers... 195% in under a month... 85% in 14 days... 176% in 5 weeks... 120% in under 3 months... 55% in two days... 138% in 8 days... And even 222% in 8 days.

Why United Airlines (UAL) Stock Is Down 15% This Week

United Airlines shares are trading lower by 15% since Monday's open. The stock is down amid rising trade tensions, higher costs and global uncertainty.

Oregon police investigate nighttime gunshots that shattered windows at a Tesla dealership

PORTLAND, Ore. (AP) — Police in Oregon said Thursday they are working with the FBI to investigate gunshots fired at a Tesla dealership overnight in the latest instance of vandalism at one of the company's retail stores.

The Fort Knox Cover-up? What It Means for Gold - Ad

Trump and Musk are demanding answers: Is Fort Knox empty? If the gold is gone, supply collapses, and prices could skyrocket instantly. Right now, I've uncovered 5 major gold predictions that could make this Fort Knox moment even bigger than people realize. One of them is already unfolding--and the window to act is closing fast.

Sam Bankman-Fried Says Prison Inmate Diddy Has Been 'Kind' To Him: 'It's A Position No One Wants To Be In'

Jailed cryptocurrency fraudster Sam Bankman-Fried shared his prison experience and interaction with fellow inmate rapper Sean Combs, popularly known as "Diddy," according to an interview released Thursday.

Elon Musk's SpaceX Successfully Catches Super Heavy Booster With 'Mechazilla,' But Starship Upper Stage Lost In Test Flight

SpaceX marked a significant advancement in rocket reusability on Mar. 7 when the launch tower successfully caught its Super Heavy booster during Starship's eighth test flight, though the mission ended with the loss of the Starship upper stage.

Stocks to Crash on March 16, 2026? Here's Compelling Reason Why - Ad

Perhaps no one on or off Wall Street has been more accurate calling the bull and bear turns of the past 7 years. From the bear markets of 2018 and 2022... to the roaring bull runs of 2021, 2023, and 2024. And now, Marc Chaikin is predicting the next crash will start March 14, 2026. If you have money in the markets, Chaikin's thesis is a must-see.

Microsoft Dodges UK Competition Crackdown Over OpenAI Deal, Watchdog Director Says Partnership Doesn't Get 'A Clean Bill Of Health'

Microsoft's $13 billion investment in OpenAI has escaped a formal merger investigation by the U.K.'s Competition and Markets Authority (CMA), but regulators warn that the partnership still raises potential competition concerns.

Major retailers tamper expectations for 2025 as Americans slow their spending

A pullback by American shoppers has led to more caution from national retailers about their sales potential in 2025, Abercrombie & Fitch on Wednesday becoming the latest.

Wall Street Legend Now Calling Exact Day Next Market Crash Will Start? - Ad

Perhaps no one on or off Wall Street has more accurate in calling the market turns of the past 7 years. From the bear markets of 2018 and 2022... to the roaring bull runs of 2021, 2023, and 2024. And now, Marc Chaikin is predicting the exact month (even the exact day!) the next crash is most likely to start--don't miss this huge and important new call.

Why should America worry about Trump? Try the price of eggs, say some Democrats

NEW YORK (AP) — As their party struggles to navigate the early days of Donald Trump's second presidency, some Democrats are convinced that their road to recovery lies in the price of eggs.

Palantir Cofounder Peter Thiel Might Write A Book About Ancient Prophecies, The Antichrist, And Armageddon - He Thinks We're Ignoring The Real Threat

Billionaire tech investor Peter Thiel is exploring a book on ancient prophecies, the Antichrist, and Armageddon, warning that society is ignoring the threat of a one-world government—a concern he believes demands urgent attention.

The DOGE Shock: Nine Stocks to Buy - Ad

They say that DOGE's real agenda could shock the entire stock market in the coming days - sending a handful of widely unknown stocks soaring. And they've compiled the definitive investment playbook for anyone who wants the opportunity to capitalize.

Edmunds: 2025 Honda CR-V vs. 2025 Subaru Forester

The is a redesigned model, but Subaru didn’t exactly stray from the formula of the last generation. It’s still a boxy small SUV with great visibility, adventure-ready versatility, and a no-nonsense approach to interior design. Its many upgrades for 2025 help keep it competitive, but how does it fare against the class best?

Are you owed an extra $2,105 a month in extra cash? - Ad

A little-known "loophole" has allowed a handful of regular Americans to legally collect over $109,200,000 in bonus cash. And today's your chance to join them. It doesn't matter how old you are or even how much money you make. And my research shows there's no way you can be denied from taking part in this opportunity.

Stock market today: Asian shares rebound after Trump pullback on some tariffs cheers investors

BANGKOK (AP) — Asian shares were mostly higher Thursday, tracking a rebound on Wall Street after pulled back on some of his tariffs hikes.

Canada Claps Back At 'Unjustified' Trump Tariffs On Dairy, Lumber

Canada's Trade Minister Mary Ng called the potential dairy tariffs "completely unjustified" and emphasized efforts to remove existing tariffs.

Claim the "No.1 Coin of 2025" Before March 24th - Ad

After spotting 44 different coins that have returned over 100%...Chris Rowe is now exposing the details behind the "Superpower Coin"... that's partnered with 19 of the largest companies from some of the world's largest superpower nations... A little-known 3-cent coin that is poised to outperform Bitcoin in 2025... starting on March 24th.

Iranian government official who was key to 2015 nuclear deal resigns under hard-liner pressure

TEHRAN, Iran (AP) — A former Iranian foreign minister who was key to the country's 2015 nuclear deal with world powers reportedly tendered his resignation on Monday from the government of reformist , caving in to pressure from hard-liners.

Trending Now

Information, charts or examples are for illustration and educational purposes only and not for individualized investment management This message contains commercial elements, such as advertising. We only send these offers to those who have opted in to our newsletter. Past performance is not indicative of future results. For these reasons we strongly suggest trading in a DEMO/Simulated account. The information provided by us is for educational and informational purposes only. We make no representations or warranties concerning the products, practices or procedures of any company or entity mentioned or recommended and have not determined if the statements and opinions of the advertiser are accurate, correct or truthful. If you use, act upon or make decisions in reliance on information contained or any external source linked within it, you do so at your own peril and agree to hold us, our officers, directors, shareholders, affiliates and agents without fault.

Copyright technicaltrading.org
Privacy Policy | Terms of Service